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Philipp Sasse

(PI; University of Bonn)

Project(s) involved: Gottschalk/Lehnart/Sasse


Curriculum vitae Philipp Sasse

Name              Jun.-Prof. Dr. med Philipp Sasse

Date of birth    07th March 1977

Nationality       German

Address           Institute of Physiology I, University of Bonn

                        Life&Brain Center, Sigmund Freud-Str. 25

                        53105 Bonn, Germany

                        Phone:             (0228) 6885 212

                        Fax:                 (0228) 6885 201



Education and academic positions

1997 – 2004                Medical education at the University of Cologne

2004                            "Approbation" (license as a medical doctor).

2007                           MD thesis “Intracellular Ca2+ oscillations: a potential pacemaking mechanism in early embryonic heart cells.” (summa cum laude).

1998 – 2004               Scientific Research as Medical Student at the Institute of Neurophysiology, University of Cologne

Dec 2004 - Jan 2010  Scientific Research as MD and Research Assistant at the Institute of Physiology 1, University of Bonn

since Jan. 2010          Assistant Professor (“Juniorprofessor”) at the Institute of Physiology 1, University of Bonn

2013                           positive mid-term evaluation of the Juniorprofessor


Research interests

Optogenetic control of the heart and other organs, pacemaking mechanisms in the embryonic and adult heart, disease-specific induced pluripotent stem cells and cardiomyocytes, in vivo imaging.


Memberships and professional functions

Member of the Biophysical Society, German Physiological Society, Young Faculty of the North Rhine-Westphalia Academy of Sciences

Reviewer for: ERC, DFG, British Heart Foundation, American Heart Association, German National Academic Foundation, Nature Biotechnology, Journal of Clinical Investigation, Circulation, Cardiovascular Research, Basic Research in Cardiology, Trends in Cardiovascular Medicine, Journal of General Physiology, American Journal of Physiology, European Journal of Physiology, Acta Physiologica, Stem Cells, Cell Stem Cell, Stem Cells and Development


Honors and awards

2001-2004      Member of the German National Academic Foundation (“Studienstiftung des deutschen Volkes”)

2008                MD thesis award of the University of Bonn

2011-2014      Member of the Young Faculty of the North Rhine-Westphalia Academy of Sciences (“Junges Kolleg der Nordrhein-Westfälischen Akademie der Wissenschaften”)”

2011                Scientific Award of the Industry Club Düsseldorf


5 most important publications

Roell W*, Lewalter T*, Sasse P* (*: shared authorships), Tallini YN, Choi BR, Breitbach M, Doran R, Becher U, Hwang SM, Bostani T, von Maltzahn J, Hofmann A, Reining S, Eiberger B, Gabris B, Pfeifer A, Welz A, Willecke K, Salama G, Schrickel JW, Kotlikoff MI, Fleischmann BK: Engraftment of connexin 43-expressing cells prevents post -infarct arrhythmia. Nature 2007; 450:819-24

Bruegmann T, Malan D, Hesse M, Beiert T, Fuegemann CJ, Fleischmann BK, Sasse P: Optogenetic control of heart muscle in vitro and in vivo. Nature Methods 2010;7:897-900.

Beiert T, Bruegmann T, Sasse P: Optogenetic activation of Gq-signaling in cardiomyocytes modulates pacemaker activity. Cardiovasc Res. 2014; 102:507-516

Vogt CC, Bruegmann T, Malan D, Ottersbach A, Roell W, Fleischmann BK, Sasse P: Systemic gene transfer enables optogenetic pacing of mouse hearts. Cardiovasc. Res. 2015, 106:338-43

Bruegmann T, van Bremen T, Vogt C, Send T, Fleischmann BK, Sasse P: Optogenetic control of contractile function in skeletal muscle. Nat. Commun. 2015; 6:7153