(PI; University of Bonn)
Project(s) involved: Gottschalk/Lehnart/Sasse
Curriculum vitae Philipp Sasse
Name Jun.-Prof. Dr. med Philipp Sasse
Date of birth 07th March 1977
Nationality German
Address Institute of Physiology I, University of Bonn
Life&Brain Center, Sigmund Freud-Str. 25
53105 Bonn, Germany
Phone: (0228) 6885 212
Fax: (0228) 6885 201
philipp.sasse@uni-bonn.de
Education and academic positions
1997 – 2004 Medical education at the University of Cologne
2004 "Approbation" (license as a medical doctor).
2007 MD thesis “Intracellular Ca2+ oscillations: a potential pacemaking mechanism in early embryonic heart cells.” (summa cum laude).
1998 – 2004 Scientific Research as Medical Student at the Institute of Neurophysiology, University of Cologne
Dec 2004 - Jan 2010 Scientific Research as MD and Research Assistant at the Institute of Physiology 1, University of Bonn
since Jan. 2010 Assistant Professor (“Juniorprofessor”) at the Institute of Physiology 1, University of Bonn
2013 positive mid-term evaluation of the Juniorprofessor
Research interests
Optogenetic control of the heart and other organs, pacemaking mechanisms in the embryonic and adult heart, disease-specific induced pluripotent stem cells and cardiomyocytes, in vivo imaging.
Memberships and professional functions
Member of the Biophysical Society, German Physiological Society, Young Faculty of the North Rhine-Westphalia Academy of Sciences
Reviewer for: ERC, DFG, British Heart Foundation, American Heart Association, German National Academic Foundation, Nature Biotechnology, Journal of Clinical Investigation, Circulation, Cardiovascular Research, Basic Research in Cardiology, Trends in Cardiovascular Medicine, Journal of General Physiology, American Journal of Physiology, European Journal of Physiology, Acta Physiologica, Stem Cells, Cell Stem Cell, Stem Cells and Development
Honors and awards
2001-2004 Member of the German National Academic Foundation (“Studienstiftung des deutschen Volkes”)
2008 MD thesis award of the University of Bonn
2011-2014 Member of the Young Faculty of the North Rhine-Westphalia Academy of Sciences (“Junges Kolleg der Nordrhein-Westfälischen Akademie der Wissenschaften”)”
2011 Scientific Award of the Industry Club Düsseldorf
5 most important publications
Roell W*, Lewalter T*, Sasse P* (*: shared authorships), Tallini YN, Choi BR, Breitbach M, Doran R, Becher U, Hwang SM, Bostani T, von Maltzahn J, Hofmann A, Reining S, Eiberger B, Gabris B, Pfeifer A, Welz A, Willecke K, Salama G, Schrickel JW, Kotlikoff MI, Fleischmann BK: Engraftment of connexin 43-expressing cells prevents post -infarct arrhythmia. Nature 2007; 450:819-24
Bruegmann T, Malan D, Hesse M, Beiert T, Fuegemann CJ, Fleischmann BK, Sasse P: Optogenetic control of heart muscle in vitro and in vivo. Nature Methods 2010;7:897-900.
Beiert T, Bruegmann T, Sasse P: Optogenetic activation of Gq-signaling in cardiomyocytes modulates pacemaker activity. Cardiovasc Res. 2014; 102:507-516
Vogt CC, Bruegmann T, Malan D, Ottersbach A, Roell W, Fleischmann BK, Sasse P: Systemic gene transfer enables optogenetic pacing of mouse hearts. Cardiovasc. Res. 2015, 106:338-43
Bruegmann T, van Bremen T, Vogt C, Send T, Fleischmann BK, Sasse P: Optogenetic control of contractile function in skeletal muscle. Nat. Commun. 2015; 6:7153